Pebrine disease is a traditional and destructive disease in sericulture.The causative agent is Nosema bombycis.

• 家蚕（Bombyx mori）微粒子病作为传统养蚕业上一种既古老而又具毁灭性的传染性疫病，其致病病原为家蚕微粒子孢子（Nosema bombycis，简称N.；b）。