Patients at very high risk for recurrent ulcer bleeding who need anti-inflammatory analgesics should receive combination treatment with a COX 2 inhibitor and a PPI.

• 当患者需氧抗炎镇痛治疗会有高风险的复发性溃疡出血，应该接受环氧化酶-2(COX-2)抑制剂和质子泵抑制剂的联合治疗。