Pathological changes of the organization, mainly the epidermal cuticle significant parakeratosis, acanthosis cell layer thickening, epidermal sudden downward extension of in-depth dermis.

• 本型组织病理改变，主要是表皮角质层有显著角化不全，棘细胞层增厚，表皮突向下延展，深入真皮。