PTP BAS is a cytoplasmic PTP that has been originally cloned from a human basophilic leukaemia cell line by Maekawa and his colleagues in 1994. PTP BAS is expressed in various human tissues, especially in the kidney, lung and fetal brain at high levels.

• PTP BAS基因为编码具有蛋白酪氨酸磷酸酶活性的基因，1994年，Maekawa等最早将PTP BAS从人类嗜碱性粒细胞白血病的细胞株中克隆出其全长cDNA，并发现PTP BAS在多种人种组织中表达，特别是在肾脏、肺和胎脑中呈高表达。