PTEN brings into its lipid and protein phosphatase activity through PIP_3,FAK,MAPK pathway. PTEN also induces apoptosis,inhibites cell growth,regulates cell migration and adhesiveness.

• PTEN通过PIP3途径、FAK途径、MAPK途径等发挥其脂质磷酸酶和蛋白磷酸酶活性,诱导细胞凋亡、抑制细胞生长、调节细胞迁移与黏附;