PGE 1 nebulization can selectively dilate pulmonary vascular, reduce MPAP and PVR of oleid-acid induced ALI dog models, and rapidly improve PaO 2 and PaO 2/FiO 2 without affecting systemic hemodyanmic.

• 雾化吸入PGE1 可选择性扩张肺血管 ,降低油酸型ALI犬MPAP和PVR ,迅速提高PaO2 /FiO2 ,且不影响体循环