PGD2 then interacts with DP receptors (DPR) in the chemosensory region of the ventro-medial surface of the rostral basal forebrain to initiate the signal to promote sleep probably via the activation of adenosine A2a receptive neurons.

• 循环中的PGD2可与前脑头端基底腹内侧面的化学感受器中的前列腺素D2受体(DPR)相互作用,通过活化具有腺苷A2a。 受体的神经元以产生促进睡眠的信号。