P-methoxybenzeneacetonitrile was prepared in 34. 8% yield starting from anisole, via chloromethylation, cyanogenation and fractional distillation.

• 以苯甲醚为原料；经过氯甲基化；氰化反应后；通过精馏获得对甲氧基苯乙腈；总收率为34.；8%25。