Overproduction of reactive oxygen species(ROS) under pathophysiologic condition is crucial in the development of cardiovascular diseases.The major source of ROS is from NADPH Oxidase(NOX).

• 活性氧的增加与心血管疾病密切相关,而产生活性氧的主要酶体是尼克酰胺腺嘌呤二核苷酸氧化酶(NADPH氧化酶)。