Our work has demonstrated that the PML breakpoints in APL patients are clustered in two limited regions, PML-bcrl and PML-bcr2, separated from each other by about 10 kb.

• 我们以前的工作证明APL患者中PML基因断裂点集中于2个有限区域,即PMLbcr 1和PML-bcr 2,二者相距约10kb。