Our study proved the general secretory (Sec) pathway play important role in protein secretion by Streptococcus mutans, and there is great difference in the expression of secA between plantonic and biofilm condition.

• 实验证实Sec分泌途径在变形链球菌的蛋白分泌中发挥重要的作用,并且sec蛋白在变形链球菌不同生长状态下的表达有显著差异。 在生物膜状态下,变形链球菌毒力因子的分泌明显增加。