Our study demonstrated that the implementation of national health insurance program may play an important role in the decrease of both prevalence and incidence rates of thalassemia major in Taiwan.

• 本研究显示台湾罹患重型乙型海洋性贫血病患于全民健保实施后明显减少，而对于重型乙型海洋性贫血病患的照顾虽有进步，但仍有努力的空间。