Observed twelve weeks and their blood glucose(BG), blood urea nitrogen(BUN), serum creatinine(Scr), kidey weight to body weight (KW/BW), creatinine clearance(Ccr) and 24- hour urinary protein (24Upro) were detected.

• 观察12周后,检测大鼠血糖(BG)、血尿素氮(BUN)、血肌酐(Scr)、肾脏肥大指数(肾重KW/体重BW)、肌酐清除率(Ccr)和24h尿蛋白(24Upro)。