Objective:The present study was designed to detect anti?fibrotic effects of low dose aldosterone(ALDO) receptor anatagonist?spironolactone (spiron) on the sustained hypertensive myocardial fibrosis induced by LNNA.

• 目的：探讨小剂量醛固酮受体拮抗剂安体舒通抗左旋硝基精氨酸（LNNA）诱导高血压心肌纤维化的可行性。