Objective: To modify orthotopic liver transplantation in rats; to unravel the mechanism and the impact of cold ischemia on early acute rejection in rat liver allografts.

• 目的：探讨大鼠原位肝移植模型的技术改进；对冷缺血时间与肝移植术后早期急性排斥反应进行相关性研究，探讨其中的免疫学机制。