Objective: To investigate the effect of hypoxia on the mRNA expression of tissue inhibitor of metalloproteinases (TIMPs) in breast carcinoma cell line (MDA-231) and the effect of basil polysaccharide (BP) on the expression of TIMPs.

• 目的:探讨低氧对人乳腺癌细胞株MDA-231金属蛋白酶组织抑制剂(TIMPs)mRNA表达的影响,以及罗勒多糖(basilpolysaccharide,BP)对TIMPs的作用。