Objective: To explore the therapeutic value of HSV tk expression in the presence of B7 in treatment of breast cancer. Methods: We genetically modified Line SHZ 88, a mammary cancer line.

• 目的：探讨单纯疱疹病毒胸苷激酶基因（HSV－tk）、B细胞活化抗原（B7）联合基因治疗乳腺癌的协同性。