Objective: To challenge the previously proposed anticancer mechanism of nitidine chloride, which suggest there exist anti-tumor C(6)=N(5) double bond structure.

• 目的:通过两面针碱在碱溶液中的反应实验，对文献报道的氯化两面针碱可能存在C（6）=N（5）双键结构高反应活性的抗癌机制提出质疑。