Objective To study the protective effect and immune response type of mice induced by calpain DNA vaccine and one or more unmethylated CpG oligodeoxyuncleotides (CpG-ODN).

• 目的 探讨含非甲基化CpG单核苷酸 (CpG ODN)协同calpainDNA疫苗抗日本血吸虫感染的保护性作用、诱导的免疫应答类型及其免疫机理。