Objective To study the exons deletion mechanisms for dystrophin gen e, the molecular characters of breakpoints of junction fragments for deletion-t y pe Duchenne muscular dystrophy (DMD) patients with 46 and 51 exons deletion were compared and analyzed.

• 目的 对比分析缺失型杜氏肌营养不良症 (Duchenne muscular dystrophy,DMD)缺失热区第 46号和 51号外显子缺失后形成的连接片段的断裂点的分子结构特点 ,以研究 DMD基因外显子的缺失机理。