Objective To study selective killing effect of herpes simplex virus-thymidine kinase/ganciclovir(Hsv-tk/GCV) driven by human telomerase catalytic subunit (hTERT) promoter on lung cancer cell line A549 in vitro.

• 目的研究人端粒酶催化亚单位(human telomerase catalytic subunit,hTERT)基因启动子调控单纯疱疹胸苷激酶/更昔洛韦(herpes simplex virus-thymidine kinase/ganciclovir,Hsv-tk/GCV)治疗系统对人肺癌细胞株A549的选择体外杀伤作用。