Objective To observe the expressive changes of angiopoietins(Ang)/Tie-2 axis and vascular endothelial growth factor (VEGF) in kidney tissue and examine the correlation of Ang/Tie-2 axis and VEGF with renal microvascular disease in diabetic rats.

• 目的探讨血管生成素(Ang)及其受体(Tie-2)和血管内皮生长因子(VEGF)在糖尿病肾脏中的表达变化规律,研究其与肾脏微血管结构变化的关系。