Objective To observe cytogenetic and molecular genetic mechanism of acute promyelocytic leukemia(APL) switching to acute monocytic leukemia (AML-M5).

• 目的探讨儿童急性早幼粒细胞白血病(APL)治疗后转为急性单核细胞白血病(AML-M5)的细胞遗传学和分子遗传学机制。