Objective To investigate the in vitro susceptibilities of HSV-2 clinical strains isolated in Nanjing to acyclovir ( ACV ) and valaciclovir ( VCV ), and to develop a plaque assay to purify ACV-resistant HSV isolates.

• 目的测定南京地区收集的15株单纯疱疹病毒2型(HSV-2)对阿昔洛韦和伐昔洛韦的敏感性,初步建立空斑法提取阿昔洛韦耐药株。