Objective To evaluate the tetrahydrobiopterin(BH 4) metabolism,gene mutation and clinical manifestation in patients with dopa responsive dystonia(DRD).

• 目的 探讨多巴反应性肌张力障碍 (DRD)其四氢生物蝶呤 (BH4)代谢及基因突变与临床表型关系。