Objective To establish reversed phase HPLC method for simultaneous determination of the concentration of carbamazepine(CBZ)and diltiazem(DZ) in serum,using diazepam as internal standard.

• 目的建立反相高效液相色谱(HPLC)法,以安定为内标,同时测定血清中卡马西平(CBZ)和地尔硫(DZ)的浓度。