Objective To construct a kind of engineered cells that can secrete human glial cell line derived neurotrophic factor (GDNF) and study its possible effects on genetic therapy of Parkinsons disease.

• 目的 构建携带大鼠胶质细胞源性神经营养因子(GDNF)基因的真核细胞表达载体，为应用GDNF进行如帕金森综合征之类的神经元退化性疾病的基因治疗打基础。