Objective To construct DNA double strand break(DSB) repair protein hKu70 deficient cell strain and to observe its biological characters for studying the functions of hKu 70 gene and the effects of occupational harmfulness factors on DSB repair.

• 目的 建立并鉴定DNA双链断裂 (DSB)修复蛋白hKu70缺陷细胞株 ,并观察该缺陷细胞的某些生物学效应 ,用于hKu70基因功能及职业有害因素对DNA双链断裂修复影响的研究。