Objective To apply a real-time fluroscent PCR assay for detecting MDM 2 mRNA expression in acute granulocytic leukemia (AML) and study the correlation of MDM 2 mRNA with pathogenesis, FAB classification and treatment outcome.

• 目的 应用实时荧光PCR技术 ,检测癌基因MDM2 在急性粒细胞白血病 (AML)中的表达并分析其与AML发生、分型及疗效的关系。