ONYX-015, a ElB-deleted adenovirus mutant replicates efficiently in p53-abnormal cells and results in the lysis of the tumors, but do not do so in p53-normal cells.

• 一种腺病毒E1B缺失体ONYX-015能够在p53突变的肿瘤细胞内有效地复制而导致痛细胞的裂解,但不能在p53正常的细胞内复制。