OBJECTIVE: The renal interstitial fibrosis(RIF) is almost the common pathway by which all the various chronic kidney diseases (CKD) progress to end stage renal disease(ESRD).

• 目的：肾间质纤维化(RIF)是各种不同病因的慢性肾脏病(CKD)随着病程进展进入终末期肾病(ESRD)的一个进行性、不可逆的共同途径。