Natural carotene has been successfully micronized from dichloromethane solutions using CO_2 as antisolvent by the particle formation method of Solution Enhanced Dispersion by Supercritical Fluids(SEDS).

• 以二氯甲烷为溶剂；超临界CO2为抗溶剂；采用超临界流体强制分散溶液技术成功地对天然胡萝卜素进行了超细化.