Multidrug resistance(MDR) has become the main hindrance of chemotherapy,and the reversal of MDR is the key point to improve curative effect of chemotherapy.

• 摘要 肿瘤细胞对化疗药物产生的多药耐药(MDR)已成为当前影响肿瘤化学治疗疗效的主要障碍,寻找低毒有效的MDR逆转剂是提高化疗疗效的关键。