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- Methods:We constructed Mycobacterium tuberculosis MPT64 antigen DNA vaccine(pM)and ubiquitin-MPT64 fusion gene DNA vaccine(pUM). 目的:用遍在蛋白质调节结核杆菌单一抗原DNA疫苗,以期获得更强的免疫保护。
- Immunotherapy with a chimeric AFP and HSP70 gene DNA vaccine targeting on a murine hepatocellular carcinoma 甲胎蛋白与热休克蛋白70融合DNA疫苗抗肿瘤免疫
- Immune response induced in mice by codelivery of interleukin-18 recombinant and HBV S gene DNA vaccine IL-18重组体联合HBVS基因核酸疫苗免疫小鼠的实验
- The Immunogenicity and Protective Immunity of Mip Gene DNA Vaccine Against Legionella Pneumophila 嗜肺军团菌mip基因DNA疫苗初步研究
- Objective To construct a multivalent DNA vaccine. 目的构建日本血吸虫多价DNA疫苗。
- The use of DNA vaccine for the induction of mucosal immunity are reviewed. 现主要就DNA疫苗的黏膜免疫进展作一综述。
- There are many routes of DNA vaccine immunization, including intramuscular injection,intradermal injection,subcutaneous injection,gene gun immunization, mucosa immunization, and so on. 核酸疫苗的接种有多种途径,包括肌内、皮内、皮下注射途径、基因枪免疫、黏膜免疫途径等。
- All these suggested that porcine IL 6 gene and CpG motifs could be employed as effective immunoadjuvant to raise the humoral and cellular immune responses of animals to DNA vaccine. 证明VPIL 6和CpG序列能显著增强动物对DNA疫苗的细胞和体液免疫反应 ,可作为高效的基因免疫增强剂
- In this paper, the research in optimization design for DNA vaccine was reviewed, including choice of antigen gene and immune adjuvant, optimization of plasmid vectors and inoculation methods. 许多试图增强和调节质粒DNA疫苗的免疫原性和效率的方案都在研究之中。
- In order to screen out YAC clones in the CEPH YAC library related to a definite gene DNA fragment or locus, we need to establish a screening system. 摘要 为了在知道某个区域、位点、基因或DNA片段的部分信息后,能从CEPH YA C库中筛选出与其对应的YAC克隆,为进一步研究奠定基础,需要建立一个筛选体系。
- CONSTRUCTION AND IMMUNE RESPONSE OF A DNA VACCINE VECTOR?EXPRESSING HEAT SHOCK PROTEIN 70 OF ?LEISHMANIA DONOVANI? 杜氏利什曼原虫热休克蛋白70的DNA疫苗表达载体构建及体内应答研究
- This paper summarized the research advance in the live attenuated vaccine,sporozoite vaccine and DNA vaccine. 综述了减毒活疫苗、子孢子疫苗和核酸疫苗的研究进展。
- To construct a therapeutic HBV DNA vaccine and investigate its expression in mammalian cells. 摘要目的构建一种治疗性的乙肝DNA疫苗并测定它的表达。
- This article summarizes the present research tatus and applied prospects in tuberculosis DNA vaccine. 本文概述了结核病DNA疫苗研究的现状及其应用前景。
- DNA vaccine can induce potent humoral and celluar immune respondses in numerous animals. DNA做为一种新型的疫苗在免疫人和动物后可以引起强烈的体液免疫和细胞免疫。
- Therefore,pTL-8/AMA-l(rtTA) combined with pUHS6-l is a good regulable DNA vaccine candidate against Plasmodium falciparum. pTL一8/AMA一1(rtTA)附加 pUHS6一构成了可调控的DNA免疫系统。
- Both CpG motifs and pIL-2 have positive effects on the production of the antibody in mice post-injected CEA DNA vaccine. CpG基序和IL - 2表达质粒对DNA疫苗产生抗体有促进作用
- This article summarizes vaccine construction、principle、adjuvant、inoculability、safety, present problem and prospect of DNA vaccine applications. 就DNA疫苗的构建、作用原理、佐剂、接种方法、安全性、目前存在的问题及应用前景作一综述。
- The present researches have pointed out that HBV DNA Vaccine will become a new vaccine to prevent and treat Hepatitis B in the future. 目前研究认为,乙型肝炎DNA疫苗很可能成为预防和治疗乙型肝炎的全新一代疫苗。
- They found three doses of DNA vaccine given by tattooing produced at least 16 times higher antibody levels than three intramuscular injections. 他们发现3种剂量DNA疫苗,通过纹身产生的抗体水平比普通的肌肉注射至少高16倍。