Model group was fed with 3% DSS solution ad libitum for 5 days and followed by distilled water for 3 weeks to induce a colitis model, which progressed from the acute to chronic stage.

• 模型组自由饮用3%25DSS溶液，5d后改饮用蒸馏水3周，建立急性结肠炎慢性化模型。