Micronuclei assay of hone marrow and variation of testicles weight/body weight menifests hereditary toxicity, shows dose-effect relationship and be under positive groups;

• 骨髓微核试验和睾丸／体重比变化分析均显示中间剂量组和治疗剂量组有不同程度的遗传毒性，且存在剂量-效应关系，但小于阳性对照；