MethodsThe conditioned place aversion (CPA) was used to establish the negative affection induced by withdrawal from acute morphine dependence in rats.

• 方法以条件性位置厌恶(CPA)实验建立急性吗啡依赖大鼠戒断性情绪反应模型,观察大鼠训练前后在“纳络酮匹配侧”停留时间的变化。