Methods:The senescent mice induced by D-galactose,SDH and LDH,LPF were detected by the histochemical method,and the histological changes were synchronously observed by electronic microscope.

• 方法:D-半乳糖制作小鼠衰老模型,组织化学方法观察小鼠脑组织琥珀酸脱氢酶(SDH)、乳酸脱氢酶(LDH)、脂褐素(LPF)的变化,同步观察电子显微镜下的组织学变化。