Methods:The reversal effects of quinine(Quin) in combination with cyclosporin A (CsA),dipyridamole (DPM) or tamoxifen(Tam),respectively on the drug resistance of K562/HHT were studied by MTT,flow cytometry and median?effect principle.

• 方法：用MTT法、联合效应分析和流式细胞仪测定技术研究奎宁（Quin）分别与环孢菌素A（CsA）、他莫西酚（Tam）、潘生丁（DPM）联合逆转耐药细胞系K562/HHT对柔红霉素（DNR）和高三尖杉酯碱（HHT）耐药。