Methods:The expression of P16 protein was detected in 30 cases of breast carcinoma, 20 cases of breast fibroadenoma and 20 cases of normal breast tissue by immunohistochemistry.

• 方法:应用免疫组化方法检测30例乳腺癌、20例乳腺纤维腺瘤、20例正常乳腺组织中P16蛋白的表达情况。结果:P16蛋白在乳腺癌组织表达阳性率为46。