Methods:Bone marrow mononuclear cells(MNCs) from 10 newly diagnosed Ph chromosome positive CML patients in chronic phase were separated and cultured in vitro for 10 days.

• 方法 :分离 10例初诊的慢性期Ph+ CML患者骨髓单个核细胞 (MNC) ,体外培养 10天 ,利用染色体分析法检测培养前后Ph+ 中期细胞比例 ;