Methods:An ADM-resistant human colon carcinoma cell line SW480/ADM was induced by continuously exposing human colon carcinoma cell line SW480 to gradually increasing doses of Adriamycin(ADM).

• 方法:应用人结肠癌细胞系SW480，以递增阿霉素（ADM）浓度的方法，体外连续培养建成一株SW480/ADM。观察该细胞生长规律。