Methods:After periodontitis canine model was established and received roughtine treatment, then GTR operation with absorptive collagen membrane was performed on a side of the body.

• 方法:采用钢丝结扎和去骨法,人工建立狗的牙周炎模型,牙周常规治疗后,使用可吸收性胶原膜进行GTR术,采用同体对照法,对侧行单纯翻瓣术,不放置诱导膜。