Methods:80 male Wistar rats were randomly divided into normal group,control group,GNI group and estrogen group, 20, 20, 25, 15 each group.

• 方法:将80只3月龄雌性Wistar大鼠随机分为4组:正常对照组、模型组、中药组和西药组,每组分别为20,20,25,15只。