Methods:1 Test of the maximal tolerance dose:20 Kun Ming mice in health,which weigh 20 + 5 g were administed at doses of 5.94g/20g for two times .

• 1 最大耐受量实验：选用健康昆明种小鼠20只，雌雄各半，体重为20±5g，分别给予加味甘麦大枣汤煎剂(5.；94g/20kg)1ml灌胃，每天2次；