Methods: Wistar rats were subjected to sepsis induced by cecal ligation and puncture (CLP), and the rats were randomly divided into the normal control, septic group. They were sacrificed at 2h, 3h, 4h, 5h after CLP.

• 方法:将30只大鼠随机分为5组,其中6只作为对照组,另外24只采用盲肠结扎穿孔术(CLP)致脓毒症模型,于术后2h、3h、4h、5h时限分为4组作为实验组。