Methods: The contents of evodiamine and rutaecarpine in Fructus Evodiae were determined with HPLC, and the total yields of the two alkaloids were chosen as the evaluating indicator.

• 方法:采用HPLC法测定吴茱萸碱和吴茱萸次碱的含量,以两种生物碱总含量为评价指标,采用正交试验设计确定最佳甘草制吴茱萸的炮制工艺。