Methods: The TK gene was transfected into human gastric carcinoma cell line MKN28 using HSV TK that packed with PA317 cell, the sensitivity of MKN28TK cells to GCV was examined in vitro .

• 方法 :应用 PA317细胞包装的逆转录病毒介导的 HSV - TK基因系统 ,在体外以逆转录病毒上清感染法将 TK基因导入 MKN2 8人胃癌细胞 ,并初步观察更昔洛韦 (GCV )对转染 TK基因的 MKN2 8胃癌细胞的杀伤作用。