Methods: Forty eight VD cases were assigned to two groups randomly: VD1 and VD2 group who were subjected to nilestrial replacement therapy or placebo treatment respectively for 4 months.

• 方法绝经后VD患者48例,随机分为VD1组和VD2组各24例,分别给予维尼安2mg与安慰剂1片口服,每月2次,治疗4个月;