Methods Thirty- six male Sprague- Dawley rats were divided into four groups:end- to- side portacaval shunt(PCS,n=10 ) ,prehepatic portal hypertension (PHPH,n=10 ) ,intrahep- atic portal hypertension (IHPH,n=8) and Sham- operated controls (SO,n=8) .

• 方法 :36只雄性 SD大鼠随机分为四组 :端侧门腔分流 ( PCS,n=10 )、肝前型 ( PHPH,n=10 )和肝内型门高压 ( IHPH,n=8)以及手术对照组( SO,n=8)。